Sodium oxybate
General English name: Sodium oxybate
Brand: xyrem
Application: Cataplexy and narcolepsy (sleep attack) in adults
Pharmaceutical forms of sodium oxibate
Sodium Oxybate Pharmacological Information
Dosage and method of taking sodium oxybate
Contraindications to sodium oxibate
Sodium oxibate intake during pregnancy and lactation
The effect of sodium oxibate on driving and working with machinery
Drug Interactions Sodium Oxybate
Special warnings and precautions while taking sodium oxibate
Side effects of sodium oxibate
Excessive use of sodium oxibate (drug poisoning)
Storage conditions of sodium oxibate
Pharmaceutical forms of sodium oxibate
Oral solution
Sodium Oxybate Pharmacological Information
A sleep attack or narcolepsy is a long-term problem that affects your sleep. Even though you feel tired during the day, your sleep at night is disturbed. Also, people with narcolepsy fall asleep suddenly during the day. Many people with narcolepsy also have cataplexy. Cataplexy is a disease in which a person suddenly loses control of some of his muscles. Sodium oxibate is used to treat narcolepsy with cataplexy. It helps reduce daytime drowsiness and relieve the symptoms of cataplexy. Sodium oxibate is sometimes used in combination with other drugs to treat narcolepsy.
Dosage and method of taking sodium oxybate
Carefully read the package leaflet before starting treatment with sodium oxybate. This brochure will help you to get comprehensive information about the drug and its possible side effects.
The dose and amount of sodium oxibate varies from person to person; Use the medicine exactly as your doctor advised. Two doses of 100 and 200 mg of sodium oxibate are produced. Sodium oxibate should usually be taken in two doses, one dose just before bedtime and the second dose 4-2.5 hours after bedtime.
If you forget to take the first dose of your medicine at the right time, take it at any time until near the second dose of the medicine, and then use the second dose of the medicine; If you miss a second dose, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.
Contraindications to sodium oxibate
Note the expiration date of Sodium Oxibate and do not take it if it has expired.
Never give sodium oxibate to another person, even if you have the same symptoms.
Check for drug interactions, and if you are taking a drug that interacts with this medication, talk to your doctor about using your medications.
Sodium oxibate intake during pregnancy and lactation
During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.
The effect of sodium oxibate on driving and working with machinery
People with sleep apnea need a legal license to drive and work with vehicles. After taking sodium oxibate, your symptoms may be well controlled and you may be allowed to drive with the necessary tests. However, for driving, you need regular check-ups and a doctor's advice.
Sodium oxibate may make you feel dizzy and drowsy. Make sure you are fully conscious before driving.
Drug Interactions Sodium Oxybate
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
The specific medications listed below can increase the risk of side effects from sodium oxibate (such as slow breathing, severe drowsiness, and dizziness) if medications such as alcohol, sleeping pills, or anti-anxiety medications (such as salplon, benzodiazepines) are used. Tell your doctor or pharmacist if you are taking diazepam, zolpidem, s-zopiclone, barbiturates (such as pentobarbital), muscle relaxants, and painkillers (such as codeine).
Special warnings and precautions while taking sodium oxibate
Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best to let your doctor know the following before taking the medicine:
- If you are pregnant or planning to become pregnant, or if you are breast-feeding.
- If you have any kidney or liver problems.
- If you have a cardiovascular problem.
- If you have trouble breathing.
- If you have porphyria (hereditary blood disorder).
- If you have high blood pressure.
- If your diet is low in salt due to a specific illness.
- If you have a history of drug abuse.
- If you have a mental illness or depression.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Side effects of sodium oxibate
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:
Headache: Ask your doctor to prescribe a suitable painkiller. If your headache persists, talk to your doctor.
Feeling sick, sick: Eat simple, spicy foods.
Feeling dizzy or tired: Be careful when using tools or machines.
Consult your doctor if you have any other symptoms that you feel are due to the use of sodium oxibate.
Excessive use of sodium oxibate (drug poisoning)
Do not take more than the dose prescribed by your doctor.
If you feel that someone has a drug poisoning and you have symptoms such as lack of reaction, slow breathing, inability to control urination or defecation, shortness of breath or fainting, and weakness (fainting), call the emergency room right away.
Storage conditions of sodium oxibate
- Keep the medicine out of the reach of children.
- Store the medicine in a cool, dry place away from heat and direct sunlight.
- A bottle of sodium oxibate solution can only be stored for 40 days, after which time the remaining medicine must be discarded.
- The diluted solution of this medicine, which you prepare according to your doctor's instructions, can be stored for only 24 hours.