Semisodium valproate
General English name: Semisodium valproate
Brand: Depakote
Application: Treatment of mania associated with bipolar disorder (in adults)
Toxic Drug Information on Sodium Valproate
Contraindications to the toxic drug sodium valproate
Toxic drug interaction of sodium valproate
Tips to be considered before consuming toxic sodium valproate
Possible side effects of the toxic drug sodium valproate
Very common side effects
Common side effects
Unexplained cough and sore throat, unusual bleeding or bruising
How to store the toxic drug sodium valproate
Toxic Drug Information on Sodium Valproate
Medication Information: Bipolar disorder is a long-term illness in which you experience periods of depression (low rate) and mania or mild insanity (high rate). Toxic sodium valproate is prescribed to treat a type of mania caused by bipolar disorder. Its exact function is unknown; But they may affect the levels of certain brain chemicals that affect your mood. As a result, it keeps your mood in the normal range.
Contraindications to the toxic drug sodium valproate
- Pay attention to the expiration date of the toxic drug sodium valproate, and do not take it if the medicine you have has expired.
- Never give sodium valproate to anyone else, even if you have the same symptoms.
- Do not take more sodium valproate than the dose prescribed by your doctor.
- Check for toxic drug interactions with sodium valproate and be sure to tell your doctor what other medication you are taking.
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Toxic drug interaction of sodium valproate
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Some medications that may interact with sodium valproate toxin include certain antidepressants (eg, amitriptyline, nortriptyline, phenelzine), certain benzodiazepines (eg, clonazepam, diazepam), and certain antibiotics (such as karba). Doripenem, imipenem, mefloquine, other anticonvulsants (eg carbamazepine, ethosuximide, felbamate, lamotrigine, phenobarbital, phenytoin, ruphinamate, rufinamate, ruphinamate) , Vorinostat (vorinostat), zidovudine (zidovudine).
If your doctor prescribes low-dose aspirin (usually 325-81 mg per day) for specific medical reasons to prevent a stroke or heart attack, you should continue to take it unless your doctor tells you to stop. Give aspirin. Consult your pharmacist for more details.
If you are taking medicines that cause drowsiness, tell your doctor or pharmacist, including: alcohol, antihistamines (such as cetirizine, diphenhydramine), sleeping pills or anxiety medications (such as alprazolam), alp Diazepam, zolpidem, muscle relaxants, and analgesics and painkillers (such as codeine).
Check the labels on all your medicines (such as allergies or cough and cold medicines) because some of them are made up of substances that cause drowsiness. Ask your pharmacist how to use them so that you can use them safely.
The toxic drug sodium valproate may affect certain laboratory tests (for example, urinary ketones). Inform laboratory personnel that you have used the toxic drug sodium valproate before the test.
Tips to be considered before consuming toxic sodium valproate
Some medications cannot be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking the toxic drug sodium valproate.
- If you are pregnant or breast-feeding.
- If you or a loved one has a liver problem.
- If you have a kidney problem.
- If you have an inflammatory disease called systemic lupus erythematosus (lupus or SLE).
- If you have a rare inherited blood disease called porphyria.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Possible side effects of the toxic drug sodium valproate
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:
Very common side effects:
Feeling sick, feeling shivering
Common side effects:
Headache, diarrhea, stomach pain, increased appetite and weight, drowsiness and tiredness, thinning hair, involuntary movements, lack of concentration, allergic reactions, hearing problems, mood swings, painful periods and liver problems, changes in some test results Blood
Important Note: Toxic sodium valproate may cause serious adverse effects on blood, pancreas and liver. Although these side effects are rare, see your doctor right away if you have any of the following symptoms:
Unexplained cough and sore throat, unusual bleeding or bruising
Excessive fatigue, abdominal pain, illness, dark urine, yellowing of the skin or whites of the eyes (jaundice)
How to store the toxic drug sodium valproate
Keep all medicines out of the reach of children.
Keep the medicine in a cool, dry place away from heat and direct sunlight.