Rosiglitazone-Metformin
General English name: Rosiglitazone-Metformin
Brand: Avandamet
Application: Type 2 diabetes
Dosage forms of rosiglitazone-metformin
Rosiglitazone-Metformin Pharmacological Information
Contraindications to the use of rosiglitazone-metformin
The effect of rosiglitazone-metformin on driving and working with machines
Rosiglitazone-metformin drug interactions
Side effects of rosiglitazone-metformin
Changes in vision (such as discoloration and night vision problems)
Overdose of rosiglitazone-metformin (drug poisoning)
Storage conditions of rosiglitazone-metformin
Dosage forms of rosiglitazone-metformin
Tablet
Rosiglitazone-Metformin Pharmacological Information
Insulin is a hormone that is naturally made in the body by the pancreas. This helps control blood sugar levels. If your body does not make enough insulin to meet its needs, or if it does not use the insulin it makes effectively, a condition called type 2 diabetes (diabetes mellitus) develops. People with diabetes need treatment to control the amount of glucose (sugar) in their blood; Because good blood sugar control reduces the risk of further complications. Some people have their blood sugar controlled by dietary changes, but others, such as rosiglitazone-metformin, are prescribed to control their blood sugar.
Insulin is a hormone that is naturally made in the body by the pancreas. This helps control blood sugar levels. If your body does not make enough insulin to meet its needs, or if it does not use the insulin it makes effectively, a condition called type 2 diabetes (diabetes mellitus) develops. People with diabetes need treatment to control the amount of glucose (sugar) in their blood; Because good blood sugar control reduces the risk of further complications. Some people have their blood sugar controlled by dietary changes, but others, such as rosiglitazone-metformin, are prescribed to control their blood sugar.
Read the package leaflet carefully before starting treatment with rosiglitazone-metformin. This brochure will help you to get comprehensive information about the drug and its possible side effects.
The dose and amount of rosiglitazone-metformin varies from person to person; Use the medicine exactly as your doctor advised. The usual dose is 1-2 tablets a day. The dose of the drug depends on its effectiveness for the patient.
Take the tablet with water and with food. Try to take your dose every day, at the same time of day.
If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.
Contraindications to the use of rosiglitazone-metformin
Note the expiration date of rosiglitazone-metformin, and do not take it if your medicine has expired.
Never give rosiglitazone-metformin to another person, even if you have the same symptoms.
Check for drug interactions, and if you are taking a drug that interacts with this medication, talk to your doctor about using your medications.
Rosiglitazone-metformin during pregnancy and lactation
During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.
The effect of rosiglitazone-metformin on driving and working with machines
Rosiglitazone-metformin may cause dizziness or blurred vision, make sure you are alert before driving or operating machinery. You may have hypoglycemia due to the use of this drug and driving may not be suitable for you.
Rosiglitazone-metformin drug interactions
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Rosiglitazone-metformin may interact with insulin.
Beta-blockers (such as metoprolol, propranolol, glaucoma eye drops such as thymolol) may prevent heart palpitations, which are commonly felt during hypoglycemia. Other symptoms of low blood sugar, such as dizziness, hunger, or sweating, are not affected by these medications.
Many medications can affect your blood sugar levels and make it difficult to control your blood sugar. Before you start, stop, or change any medication, talk to your doctor or pharmacist about how to take the medicine (the medicine that works on your blood sugar level). Check your blood sugar levels regularly and consult your doctor if you notice a sudden change in your blood sugar (high or low blood sugar). If you have serious side effects, talk to your doctor about changing your medication dose, exercise program, and diet.
Special warnings and precautions while taking rosiglitazone-metformin
Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking rosiglitazone-metformin:
- If you are pregnant or planning to become pregnant, or if you are breast-feeding.
- If you have any kidney or liver problems.
- If you have a cardiovascular problem.
- If you have trouble breathing.
- If your body is swollen (edema) or your lungs are watery.
- If you have anemia.
- If you have eye (retinal) problems.
- If you have bone problems (such as osteoporosis, osteopenia).
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
- If you have a history of an allergic reaction to a drug.
Side effects of rosiglitazone-metformin
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:
Headache
Dizziness and blurred vision: These side effects can be caused by low or high blood sugar.
Symptoms of colds and coughs
Diarrhea
Vomit
Metallic taste in the mouth
joint's pain
Symptoms of hypoglycemia (hypoglycemia) such as feeling tight or anxious, sweating, feeling hungry, palpitations, dizziness: Eat sweets quickly, such as biscuits or sugary drinks, and tell your doctor if you notice any of these symptoms.
Feeling thirsty: Drink a few glasses of water every day.
Feeling nauseous (persistent vomiting), heartburn, yellowing of the skin or eyes, loss of appetite, darkening of the urine: If these symptoms bother you, see your doctor, as you may have a liver problem.
Important Note: If you notice any of the side effects listed above, be sure to tell your doctor:
Fast heartbeat or heartbeat
Changes in the menstrual cycle
Bone fracture
Changes in vision (such as discoloration and night vision problems)
Important Note: In rare cases, treatment with rosiglitazone-metformin can increase the levels of certain chemicals, such as ketones, in your blood. This can lead to a serious condition called diabetic ketoacidosis. If you notice a combination of the following symptoms in yourself, talk to your doctor immediately:
A sweet or metallic taste in your mouth or another odor in your sweat or urine
Feeling weak or sick (vomiting), abdominal pain
Rapid weight loss, feeling thirsty, abnormal or difficult breathing (shortness of breath)
Fatigue or drowsiness
Consult your doctor if you have any other symptoms that you feel may be due to the use of rosiglitazone-metformin.
Overdose of rosiglitazone-metformin (drug poisoning)
Do not take rosiglitazone-metformin more than the dose prescribed by your doctor.
Call the emergency room immediately if you feel that you have been poisoned by a drug and are experiencing symptoms such as severe hypoglycemia, severe dizziness, irregular heartbeat, shortness of breath or fainting.
Storage conditions of rosiglitazone-metformin
Keep the medicine out of the reach of children.
Store the medicine in a cool, dry place away from heat and direct sunlight.