Ramipril
General English name: Ramipril
Brand: Tritace, Triapin
Application: High blood pressure - Heart failure - Prevention of heart, kidney or vascular problems in people at risk for this disease
Pharmaceutical forms of ramipril
Combination brand containing ramipril
Ramipril Drug Information
Amount and method of taking Ramipril
Contraindications Ramipril
Contraindications Ramipril
Special warnings and precautions while taking Ramipril
Side effects of Ramipril
Overdose of ramipril (drug poisoning)
Storage conditions of Ramipril
Pharmaceutical forms of ramipril
Tablets, capsules and oral solution
Combination brand containing ramipril
Triapin: Ramipril and Fludipine
Ramipril Drug Information
Ramipril is in a class of drugs called angiotensin converting enzyme inhibitors or ACE inhibitors. It is prescribed to prevent heart failure or lower blood pressure. Hypertension is a disease in which blood pressure is higher than normal. Heart failure is a disease in which the heart does not work properly.
ACE inhibitors such as ramipril prevent the body from producing a hormone called angiotensin II. Ramipril does this by inhibiting an enzyme called an angiotensin converter. Ramipril dilates blood vessels and reduces the amount of open water absorbed by the kidneys, thereby lowering blood pressure. People with high blood pressure may have no symptoms, but if the condition persists, high blood pressure can damage the heart and blood vessels and lead to a heart attack.
Ramipril can lower blood pressure alone or in combination with other medicines. A combination brand called Triapin (Ramipril with another drug called Fludipin) can help reduce the total number of pills that people with high blood pressure need.
In heart failure, there may be too much extra fluid in the bloodstream. ACE inhibitors help reduce these fluids. These drugs have a protective effect on the heart and slow the progression of heart failure. This protective measure helps reduce the risk of cardiovascular disease in people who are at risk for these diseases.
Amount and method of taking Ramipril
- Read the package leaflet carefully before starting treatment with Ramipril. This brochure will help you to get comprehensive information about the drug and its possible side effects.
- The dose and amount of ramipril varies from person to person; Use the medicine exactly as your doctor advised. This medicine is usually given to you once a day.
- Ramipril comes in a variety of doses, with treatment usually starting at a lower dose, and it is best to start taking this medicine at bedtime so that side effects such as dizziness do not bother you.
- Try to take Ramipril at certain times of the day, you can take this medicine with or without food.
- If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.
Contraindications Ramipril
Note the expiration date of ramipril and do not take it if your medicine has expired.
Never give ramipril to another person, even if you have the same symptoms.
Try to take Ramipril at certain times of the day, you can take this medicine with or without food.
If you forget to take your daily dose at the right time but soon forget, take the medicine; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.
Contraindications Ramipril
Note the expiration date of ramipril and do not take it if your medicine has expired.
Never give ramipril to another person, even if you have the same symptoms.
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
Some medications that may interact with ramipril include aliskiren, certain immunosuppressive drugs (increased risk of infection) (such as everolimus, sirolimus), lithium, and medications that may lower potassium levels. Increase blood pressure (such as ARBs including losartan / valsartan, birth control pills containing drospirenone).
Check labels on all your medications (such as cough and cold medications, dietary supplements, nonsteroidal anti-inflammatory drugs such as ibuprofen and naproxen). Because they may contain ingredients that increase blood pressure or worsen heart failure. Talk to your pharmacist about taking Ramipril.
Concomitant use of ramipril and bee sting desensitizer (injection) can cause a very serious reaction. Tell your doctor about the use of ramipril before the injection.
Special warnings and precautions while taking Ramipril
Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to be aware of the following before taking Ramipril:
- If you are pregnant or planning to become pregnant, or if you are breast-feeding.
- If you have kidney or liver problems.
- If your body is hydrated (dehydration), for example if you have recently had diarrhea or are sick.
- If you have atherosclerosis (atherosclerosis - the deposition of fats in the walls of blood vessels).
- If you have peripheral vascular disease (a type of poor circulation).
- If you have collagen-dependent vascular disease, such as systemic lupus erythematosus (SLE) or scroderm.
- If you have cardiomyopathy (heart muscle disease), or aortic stenosis (blockage of the main artery of the heart).
- If you have ever had angioedema (swelling of the face, tongue and throat)
- If you are undergoing desensitization treatment to protect against bee and mosquito bites.
- If you have ever had dialysis treatment, or treatment in which your blood cholesterol has been removed through the device (LDL apheresis).
- If you have any problems with your heart valves or heart muscle.
- If you have a liver problem or a condition called cholestasis (obstruction of the flow of bile from the liver).
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
- If you have ever had an allergy or an unusual reaction to any of the ACE inhibitors (such as linzopril, captopril, and prindopril)
Side effects of Ramipril
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed:
- Feeling dizzy and tired
- Drowsiness
- Dry and irritating cough
- Headache
- the pain
- Symptoms similar to the common cold
- Diarrhea
- Indigestion
- Stomach ache
- Shortness of breath
- Rash and skin urticaria
- Chest pain
- Fatigue
- Change in the results of some blood tests
- Important Note: If you experience any of the following symptoms, which are rare but serious, stop taking Ramipril and tell your doctor immediately:
- Difficulty breathing, swelling of the face, mouth, tongue and throat. These symptoms are a sign of a drug allergy
- Any yellowing of the skin or whites of the eyes. These symptoms may indicate jaundice, which is a rare side effect
- Severe skin rashes
- Consult your doctor if you have any other symptoms that you feel may be due to the use of ramipril.
Overdose of ramipril (drug poisoning)
Do not take Ramipril more than the dose prescribed by your doctor.
If you feel that someone has a drug poisoning and you have symptoms such as severe dizziness, shortness of breath or fainting (fainting), call the emergency room immediately.
Storage conditions of Ramipril
Keep the medicine out of the reach of children.
Store the medicine in a cool, dry place away from heat and direct sunlight.
You can use Ramipril oral solution up to 30 days after you first opened it.