Nortriptyline

Nortriptyline

General English name: Nortriptyline

Application: Treatment of depression

Pharmaceutical forms of nortriptyline

Nortriptyline Pharmacological Information

Amount and method of taking nortriptyline

Contraindications to the use of nortriptyline

Nortriptyline during pregnancy and lactation

The effect of nortriptyline on driving and operating machinery

Nortriptyline drug interactions

Special warnings and precautions while taking nortriptyline

Side effects of nortriptyline

Nortriptyline overdose (drug poisoning)

Storage conditions of nortriptyline

 Pharmaceutical forms of nortriptyline

Tablet

 Nortriptyline Pharmacological Information

Nortriptyline belongs to a group of drugs called tricyclic antidepressants that are prescribed to treat depression. The exact cause of depression is not known. This disease can be caused for no apparent reason or by a bitter event in life or a specific disease. People with depression have a low mood and are so moody that they even have trouble doing their daily activities.

Nortriptyline can help reduce the symptoms of depression. The drug is thought to work by interfering with the function of brain chemicals (called neurotransmitters) that play a role in causing depressive symptoms.

Although nortriptyline can only be used for depression, your doctor will sometimes prescribe it to help reduce some types of nerve pain. If you have been prescribed nortriptyline for this reason, you should ask your doctor if you have any questions about your treatment.

Amount and method of taking nortriptyline

• Read the package leaflet carefully before starting treatment with nortriptyline. This brochure will help you to get comprehensive information about the drug and its possible side effects.
• The dose and amount of nortriptyline varies from person to person; Use the medicine exactly as your doctor advised. Preferably, this medicine should be taken on time and according to the doctor's prescription.
• You can take nortriptyline with a glass of water before and after a meal.
• If you forget to take your daily dose of nortriptyline at the scheduled time but soon forget to take it; But if you remember when the next dose is near the hour, do not take the missed dose. You should not take two doses of the medicine together because of the missed dose.

Contraindications to the use of nortriptyline

• Note the expiration date of nortriptyline and do not take it if the expiration date on your medicine has expired.
• Never give nortriptyline to another person, even if you have the same symptoms.
• Avoid alcohol while taking this medicine.
• Check for drug interactions with nortriptyline, and if you are using a drug that interacts with this drug, talk to your doctor about using your medications.

Nortriptyline during pregnancy and lactation

During pregnancy and lactation, you should not use the drug arbitrarily without consulting your doctor. Medications can have devastating effects on the fetus or on yourself.

The effect of nortriptyline on driving and operating machinery

Nortriptyline can make you drowsy, so make sure you are alert before driving or operating machinery.

 Nortriptyline drug interactions

Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.

Some medications that may interact with nortriptyline include arbutamine, disulfiram, thyroid supplements, and medications that can cause bleeding or bruising (including antiplatelet drugs such as clopidogrel, clopidogrel, and clopidogrel). Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, blood-thinning drugs such as warfarin, anticholinergic drugs such as benztropine, belladonna alkaloids, and certain medications for high blood pressure. Such as clonidine, guanabenz, reserpine.

Nortriptyline can cause serious drug interactions with MAO inhibitors, which can even lead to death, including MAO inhibitors (isocarboxazid), linezolid, methylene blue, Do not use phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine. Most MAO inhibitors should not be used until 2 weeks before and after starting nortriptyline.

Many drugs in addition to nortriptyline may affect heart rhythm (prolongation of QT time), including: amiodarone, dofetilide, pimozide, procainamide, quinidine , Sotalol, macrolide antibiotics (such as erythromycin).

Drugs that can affect the removal of nortriptyline from the body and affect its function include: cimetidine, terbinafine, and irregular heartbeat medications (such as quinidine / propafenone / propafenone / flecainide). flecainide), antidepressants (such as SSRIs including paroxetine / fluoxetine / fluvoxamine), although this is not a complete list; So before taking nortriptyline, make a list of all the medicines you use and share it with your doctor and pharmacist.

If you are taking medicines that cause drowsiness, tell your doctor or pharmacist, including: alcohol, antihistamines (such as cetirizine, diphenhydramine), sleeping pills or anxiety medications (such as alprazolam), alp Diazepam, zolpidem, muscle relaxants, and analgesics and painkillers (such as codeine).

If you take serotonin-boosting drugs in combination with nortriptyline, your risk of serotonin toxicity increases. Tell your doctor if you are using these referees. These include: street medications such as MDMA / "ecstasy", St. John's wort, specific antidepressants (including SSRIs such as fluoxetine / citalopram, SNRIs such as venlafaxine). Keep in mind that the risk of serotonin toxicity syndrome increases when you increase the dose of these drugs or start using these drugs.

Check the labels on all your medicines (such as allergies or cough and cold medicines) because some of them are made up of substances that cause drowsiness. Ask your pharmacist how to use them so that you can use them safely.

Nortriptyline is very similar to amitriptyline. Do not use amitriptyline-containing medicines with nortriptyline.

 Special warnings and precautions while taking nortriptyline

Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best for your doctor to know the following before taking nortriptyline:

• If you are pregnant or breast-feeding.
• If you have an overactive thyroid gland.
• If you have any liver or kidney problems.
• If you have diabetes or epilepsy.
• If you have constipation for a long time.
• If you have any urinary problems or prostate problems.
• If you have cardiovascular problems.
• If you have a history of mental health problems (for example, bipolar disorder or psychosis).
• If you have glaucoma (increased pressure in the eye).
• If you have been told that you have pheochromocytoma (a tumor in the adrenal gland).
• If you have porphyria (a rare inherited blood disorder).
• If you are currently taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines. This is especially important if you have recently been taking certain antidepressant medications (called monooxidase inhibitors (MAOIs)).
• If you have ever been allergic to any medication.

Side effects of nortriptyline

All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away after a short time of taking the medicine. In case of persistent side effects, the physician should be informed:

Nausea, indigestion, diarrhea and constipation: Eat simple foods and drink several glasses of water daily.

Blurred vision, dizziness, drowsiness: Avoid driving and working with tools in these situations.

Dry mouth: Look for sugar-free gum.

Sweating, hot flashes, difficulty urinating, change in appetite, feelings of anxiety and worry, sleep disturbance, lack of concentration, chills, itchy skin rash, weight changes, changes in sexual function, breast tenderness, changes in taste and taste of food, Ringing in the ears, rapid heartbeat: Tell your doctor if any of these bother you.

Consult your doctor if you have any other symptoms that you feel are due to the use of nortriptyline.

Nortriptyline overdose (drug poisoning)

Do not take nortriptyline more than the dose prescribed by your doctor.

If you feel that someone has been poisoned and you have symptoms such as severe drowsiness, hallucinations, rapid or abnormal heartbeat, fatigue, seizures, shortness of breath, fainting and weakness (fainting), call the emergency room immediately.

Storage conditions of nortriptyline

Keep the medicine out of the reach of children.

Store the medicine in a cool, dry place away from heat and direct sunlight.