Granisetron
General English name: Granisetron
Brand: Kytril®, Sancuso
Application: Treatment of feeling sick and nausea due to chemotherapy, radiotherapy and surgery
Drug forms of granisetron
Granistron Drug Information
Amount and method of taking granisetron
Contraindications to the use of granisetron
Granisterone use during pregnancy and lactation
The effect of granisetron on driving and working with machines
Granistron Drug Interactions
Special warnings and precautions while taking granisetron
Side effects of granisetron
Common side effects of granisetron
Rare side effects of granisetron
Excessive use of granisetron (drug poisoning)
Storage conditions of granisetron
Drug forms of granisetron
Tablets, patches, injectable vials
Granistron Drug Information
Granisterone is known as a 5HT3 receptor antagonist. This medicine is prescribed to prevent you from feeling sick. Granisterone works by blocking the action of a natural chemical in the body called serotonin, also called serotonin 5HT.
Chemotherapy and radiotherapy can increase the amount of serotonin secreted by the body. There are small receptors in the small intestine and brain called the 5HT3 receptor. Serotonin acts on these receptors and makes you feel sick. By blocking serotonin, granisterone blocks its effect on 5HT3 receptors and eliminates the feeling of sickness and nausea.
Amount and method of taking granisetron
Read the package leaflet carefully before starting treatment with this medicine. This brochure will help you to get comprehensive information about the drug and its possible side effects.
The dose and amount of granisetron varies from person to person; Use the medicine exactly as your doctor advised. The dose and form of medicine prescribed for you depends on your needs:
If you have been prescribed this medicine for surgery, you will be given the type of injection that will be given by a specialist.
If you have been prescribed this medicine to prevent nausea after chemotherapy or radiotherapy, your doctor will usually prescribe 1-2 granistron tablets (2 mg per day) daily. If you are unable to take the pill, your dermatologist will insert the patch into your body 24 hours before chemotherapy and remove it 24 hours later. This medicine may also be given to you by injection.
Contraindications to the use of granisetron
Pay attention to the expiration date of this medicine and do not take it if the medicine in your hand has expired.
Never give granisterone to another person, even if you have the same symptoms.
Check for drug interactions, and if you are taking a drug that interacts with this medication, talk to your doctor about using your medications.
Granisterone use during pregnancy and lactation
Never use this medicine during pregnancy and lactation, granisterone is extremely dangerous for pregnant women.
The effect of granisetron on driving and working with machines
Granistron can cause sleep problems, so make sure you are alert and healthy before driving or operating machinery.
Granistron Drug Interactions
Drug interactions may alter drug performance and increase the risk of serious side effects. Make a list of all the medicines (including prescription / over-the-counter and herbal medicines) you use and share them with your doctor and pharmacist. Do not change the dose of your medicine without consulting your doctor or stop taking the medicine.
In addition to granisterone, many medications may affect heart rhythm (prolongation of QT time), including amiodarone, moxifloxacin, procainamide, quinidine, sotalol. sotalol), pimozide, and macrolide antibiotics (such as erythromycin). Therefore, before using granisetron, make a list of all the medicines you use and share it with your doctor and pharmacist.
If you take serotonin-boosting drugs in combination with granisetron, your risk of serotonin toxicity increases. Tell your doctor if you are using these referees. These include: street medications such as MDMA / "ecstasy", St. John's wort, specific antidepressants (including SSRIs such as fluoxetine / paroxetine, SNRIs such as duloxetine / venlafaxine). Keep in mind that the risk of serotonin toxicity syndrome increases when you increase the dose of these drugs or start using these drugs.
Special warnings and precautions while taking granisetron
Some medications may not be prescribed under certain conditions, and some medications may be prescribed if additional treatment is needed; Therefore, it is best to let your doctor know the following before taking this medicine:
- If you are pregnant or breast-feeding.
- If you have any liver problems.
- If your heart rate is irregular.
- If you are taking certain medications. These medicines include all the medicines available, whether you are prescribed them or taking them without a doctor's prescription, such as herbal medicines and complementary medicines.
If you have a history of an allergic reaction to a drug.
Side effects of granisetron
All medications can cause side effects. But many consumers also do not experience any side effects. Some of the side effects go away shortly after taking the medicine. In case of persistent side effects, the physician should be informed.
Common side effects of granisetron
Constipation
Headache
Rare side effects of granisetron
Sleep problems
Diarrhea
Change the results of some blood tests
Important Note: Granisterone can cause problems called serotonin syndrome in some people. Although this rarely happens, see a doctor right away if you have muscle stiffness, a very high temperature (fever), a fast or irregular heartbeat.
Consult your doctor if you have any other symptoms that you feel are due to the use of granistron.
Excessive use of granisetron (drug poisoning)
Do not take more than the dose prescribed by your doctor.
If you feel that someone has been poisoned and you have symptoms such as shortness of breath, fainting and weakness (fainting), call the emergency room immediately.
Storage conditions of granisetron
Keep the medicine out of the reach of children.
Store the medicine in a cool, dry place away from heat and direct sunlight.